Centre for Operational Research and Logistics

Events and Seminars

Research Seminar

Integration of Matheuristics in Radiotherapy Planning System

The Radiotherapy Planning is a task that can be treated and optimised by Operational Research techniques. The planning involves problems that consist in determine the machine position (beam directions), the dose distribution and the multileaf collimator opening. These problems have the objective to deliver the dose prescribed in the tumor structure, and, at the same time, respect the dose limit imposed to the noble and healthy tissues. Three methodologies have been proposed to solve the dose distribution and beam directions problem: the exact method of Branch and Cut, the matheuristic GArad and the matheuristic TSrad. Computational experiments have been conducted to evaluate the methodologies performance. The case study considered is the prostate cancer, using two instances with different size of beams to be selected. The experimental results have shown a good quality solution with substantial improvement in computational time with the use of TSrad.

Biography: Thalita Monteiro Obal is from Brazil, where she works as a lecturer at Federal Technological University of Parana. She is doing her PhD in Numerical Methods in Engineering at the Federal University of Parana/Brazil. She is a visitor PhD student at University of Portsmouth from August/2014 to August/2015, under Professor Dylan Jones and Dr Djamila Ouelhadj supervision. Her research proposal is to develop an integrated system to radiotherapy planning using OR techniques.


Thalita M. Obal, Federal Technological University of Parana Brazil


Lion Gate Building, LG 2.01

Date and Time

Thu, 19 Feb 2015, 13:00 - 14:00 (BST)

For further information or any enquiries please contact our event co-ordinator, Jana Ries, at corl@port.ac.uk