Biological Sciences

Chris Read

Dr Chris Read

Senior Research Fellow

Biological Sciences

University of Portsmouth
School of Biological Sciences
King Henry Building
King Henry I Street
Portsmouth
PO1 2DY

chris.read@port.ac.uk

Profile

Research Interests

  • Protein/nucleic acid interactions and structures, (including proteins of the HMG domain family and DNA methyltransferases.
  • A wide range of biophysical and molecular biological techniques is used, including NMR and calorimetry.

Recent Publications

 

More recent publications

 

Publications Before 2008

  • Smith, M., Read, C.M. and Kneale, G.G. (2001) "Domain structure and subunit interactions in the type I DNA methyltransferase M.EcoR124I" J. Mol. Biol. 314, 41-50
  • Cary, P. D., Read, C. M., Davis, B., Driscoll, P. C. and Crane-Robinson, C (2001).
    Solution structure and backbone dynamics of the DNA-binding domain of mouse Sox-5.
    Protein Science 10, 83-98.
  • Read, C. M. and Jelesarov, I. (2001).
    Calorimetry of protein/DNA complexes and their components (Review article).
    In Methods in Molecular Biology (2nd edition). Volume 148, pp 511-533. Editor Moss, T. Published by Humana Press, Totowa, NJ.
  • Privalov, P. L., Jelesarov, I., Read, C. M., Dragan, A. I. and Crane-Robinson, C. (1999).
    The energetics of HMG box interactions with DNA: thermodynamics of the DNA binding of the HMG box from mouse Sox-5.
    Journal of Molecular Biology 294, 997-1013.
  • Crane-Robinson, C., Read, C. M., Cary, P. D., Driscoll, P. C., Dragan, A. I. and Privalov, P. L. (1998).
    The energetics of HMG box interactions with DNA. Thermodynamic description of the box from mouse Sox-5.
    Journal of Molecular Biology 281, 705-717.
  • Read, C. M. and Driscoll, P. C. (1997).
    GAGA over the nucleosome (News and Views article).
    Nature Structural Biology 4, 87-89.
  • Lnenicek-Allen, M., Read, C. M. and Crane-Robinson, C. (1996).
    The DNA bend angle and binding affinity of an HMG box increased by the presence of short terminal arms.
    Nucleic Acids Research 24, 1047-1051.
  • Read, C. M., Cary, P. D., Crane-Robinson, C., Driscoll, P. C., Carillo, M. O. M. and Norman, D. G. (1995).
    The structure of the HMG box and its interaction with DNA (Review article).
    In Nucleic Acids and Molecular Biology, Vol. 9, pp. 222-250. Editors Eckstein, F. and Lilley, D.M.J. Published by Springer-Verlag, Berlin and Heidelberg.