Biological Sciences

Profile

Roles and Responsibilities

• Reader in Environmental Biotechnology
• Erasmus coordinator
• Course Leader for MSc Applied Aquatic Biology

Qualifications

• DSci (Hons) in Organismal Biology, University of La Rochelle, France. 2007
• PhD (Hons) in Biological Oceanography and Environment, University of La Rochelle, France. 2000
• Master (Hons) in Marine Biochemistry, Ecole Pratique des Hautes Etudes, Paris, France. 1997
• Bsc (Hons) in Marine Biology, University of Western Brittany, Brest, France. 1995

Previous positions

• 2004-2005: Lecturer, University of Toulon (France)
• 2001-2004: Research Associate, University of Newcastle upon Tyne (UK)

Research interest and current program

• Natural products with biological activities
• Chemical ecology
• Marine enzyme
• Antifouling studies
• Collaborative program
• Research of new soft antifouling coatings
  • University of Le Mans, France - Prof JF PILARD & Dr JL MOUGET
• Research on new paints formulation
  • University of Toulon - DR C. BRESSY & PROF A. MARGAILLAN
• Research of new antifouling solutions without chemical
  • University of Vienna (BOKU) (Austria) - Dr G LANGERGRABER, Prof R PERFLER & Dr F KRETSCHMER
  • University of Catania (Italy) - Dr G. CIRELLI & Dr A TOSCANO
  • LIMNOS, Ljubljana (Slovenia) - Dr T BULC
• Research on bioactive new natural products
  • University of Brest, France - PROF E. DESLANDES, PROF B. CORBEL, Dr V. STIGER
  • University of Perpignan, France - DR B. BANAIGS & Dr. A SIMON-LEVERT
  • University of Toulon, France - DR C. CULIOLI
  • University of Caen - DR B. VERON
  • University of Portsmouth (UK) – Dr A SAUTREAU
  • University of Southampton (UK) – Dr L CHAMBERS & Defence Science Technology Laboratory, Salisbury (UK) – Prof K STOKES
  • University of Athens (Greece) - PROF V. ROUSSIS
  • Department of Chemistry. University College of Lahore, Lahore (Pakistan) - Prof I NAEEM
  • National Institute of Water & Atmospheric Research (NIWA), Hamilton (New-Zealand) – Dr C DEPREE
  • Department of Chemistry, Universidad Nacional de Colombia – Dr F RAMOS
• Research on chemical ecology
  • OMMM, Fort de France, Martinique (French West Indies) – DR JP. MARECHAL
  • The University of Waikaito, Hamilton (New-Zealand) – Dr M PRINSEP
  • Hong Kong University (China) - Dr H DAHMS
  • Universidade Federal Fluminense, Niteroi (Brasil) – Prof R PEIRERA & Prof B DA GAMA
  • Universidad Católica del Norte, Facultad de Ciencias del Mar, Coquimbo (Chili) – Dr C BULBOA
  • Centro Interdisciplinario de Ciencias Marinas IPN, Laboratorio de Macroalgas, La Paz, Mexico - Dr R RAMÍREZ

Funding sources

• Industrial Relevance: Contracts with leading paint company
• EU
• British Council
• OMMM, Martinique
• UNESCO
• Commonwealth
• Royal Society

Esteems indicators

• Treasurer and Member of the COIPM Executive (Comité International Permanent pour la Recherche sur la Préservation des Matériaux en Milieu Marin)

Invited Researcher:

• Universidad Católica del Norte, Facultad de Ciencias del Mar, Coquimbo, Chile. 2009
• Centro Interdisciplinario de Ciencias Marinas IPN, Laboratorio de Macroalgas, La Paz, Mexico. 2009
• Department of Chemistry. University College of Lahore, Lahore (Pakistan). 2009
• Marine Observatory of Martinique (OMMM), Martinique, West Indies. 2007
• NIWA, Hamilton, New-Zealand. 2005
• IEAPM, Arraial do Cabo, Brazil. 2005

Seminars

• 2009
  • Marine Station of National Museum of Natural History, Concarneau. France
• 2008
  • University of Baleares Islands, Spain
  • Marine Station of Banuyls, France
  • University of Palermo, Italy
  • University of Lyon 1, France
• 2007
  • University of Coventry. UK
  • LG-Sonic, Leiden, The Netherlands
• 2006
  • University of Caen Basse Normandie, Caen. France
  • Universitad Federal Fluminense, Dr. R. Pereira, Niteroi. Brazil
• 2005
  • Maine University, Le Mans, France
  • NIWA, Hamilton, New-Zealand
  • IEAPM, Arraial do Cabo, Brazil
  • Universitad Federal Fluminense, Niteroi, Brazil
• 2003
  • Integerin Biotechnology, Oban, Scotland
  • University of Western Brittany, Brest, France
• 2001
  • Marine Station of Paris VI University, Roscoff, France
• 2000
  • University of South Brittany, Lorient, France

Edition

• Editor-in-Chief of the Section Board for 'Green Chemistry' of International Journal of Molecular Sciences
• Editor of « Advances in marine antifouling coatings and technologies», pp 750 (Woodhead Publishing )ISBN 1 84569 386 8
• Editor for a special issue of Molecules “Green Chemistry and Antifouling”
• Associate Editor of International Journal of Ecology & Development (IJED)
• Associate Editor of Electronic Journal of Natural Substances (EJNS)
• Associate Editor of International Journal of Molecular Sciences (IJMS)
• Reviewer for: Aquaculture ; Biochem. Syst. Ecol. ; Biomolecular Engineering ; Bot. Mar. ; Biofouling ; Brazilian Journal of Oceanography ; Chemosphere ; Indian J. Mar. Sci. ; J. Appl. Phycol. ; J. Appl. Microbiol. ; J. Exp. Mar. Biol. Ecol. ; Lett. Appl. Microbiol. ; Mar. Env. Res. ; Sci. Tot. Env.

Conference and workshop organisation

• Member of International Committee for the organisation of the European Society of Marine Biotechnology ( ESMB) Conference 2009 “Marine Biotechnologies in the marine value chain” (Concarneau, France)
• Member of the organisation committee of the 14th International Congress on Marine Biofouling and Corrosion to be held in Kyoto (Japan, 2008)
• Organisation of a workshop for the ChemFree EU project: Development of a chemical-free water treatment system through integrating fibre filters, ultrasound and UV-C. Portsmouth (UK, 2007)
• Chairman for the "Macrofouling" session of the 12th International Congress on Marine Corrosion and Biofouling. Southampton (UK). 2004
• Organisation of a workshop entitled "Biofouling, what's next?" (International Marine Biotechnology Congress, Townsville, Australia). 2000

Participation in Jury

• PhD thesis
  • R BABU, University of Bharathiar, Tamil Nadu, India. 2008
  • R JELLALHI, University of Maine, Le Mans, France. 2008
  • M PARENTE, University of Portsmouth, 2007
  • E PLOUGUERNE, University of Western Brittany, France, 2006
  • A BAZES, University of South Brittany, France, 2006
• Master thesis
  • M DAVIES, University of Portsmouth 2008
  • K LEBRET, EPHE, Concarneau, France. 2008
  • M SEBIRE, EPHE, Montpellier, France. 2005

Scientific production

Recent Publications

More recent publications

Publications Before 2008:

• 2007:
  • C HELLIO, et al. Demonstration of a true phenoloxidase activity and activation of a ProPO cascade in Pacific oyster, Crassostrea gigas (Thunberg) in vitro. Fish Shellfish Immunol. 22: 433-440
  • M TSOUKATOU et al. Evaluation of the activity of the sponge metabolites Avarol and Avarone and their synthetic derivatives against fouling micro- and macroorganisms. Molecules. 12: 1022-1034
• 2005:
  • C HELLIO, et al. Inhibitory Effects of Mediterranean Sponge Extracts and Metabolites on Larval Settlement of the Barnacle Balanus amphitrite. Mar. Biotech. 7: 297-305
• 2004:
  • C HELLIO, et al. Seasonal variation of antifouling activities of marine algae from Brittany Coasts (France). Mar. Biotechnol. 6: 67-82
  • C HELLIO, et al. Amino acid utilization by the unicellular alga Chlamydomonas reinhardtii: specific study of histidine. PPB. 42: 257-264
  • C HELLIO, et al. Anti-settlement activities of Grateloupia turuturu hydroalcoholic extracts on cyprids of Balanus amphitrite. Biofouling. 20:139-145
  • JP MARECHAL, et al. Seasonal variations in antifouling activity of crude extracts of the brown alga Bifurcaria bifurcata against cyprids of Balanus amphitrite and the marine bacteria Cobetia marina and Pseudoalteromonas haloplanktis. J. Exp. Mar. Biol. Ecol.. 313: 47-62
  • JP MARECHAL, et al Video-tracking of cyprid of Balanus amphitrite settlement behaviour. Biofouling. 20: 211-217
• 2002:
  • M TSOUKATOU et al. Chemical defense and antifouling activity of three mediterranean sponges of the genus Ircinia. Z. Naturforsch. 57C: 161-172
  • C HELLIO et al. Antibacterial, antifungal and cytotoxic activities of extracts from fish epidermis and epidermal mucus. Int. J. Antimicrob. 20: 220-225
  • F ZENTZ, et al.`Antifouling activities of N-substituted maleimides and succinimides : antibacterial activities and inhibition of Mytilus edulis phenoloxidase. Mar. Biotechnol. 4: 434-440
  • C HELLIO, et al. Effect of extracts of marine algae on the anti-settlement activities against diatoms and spores of macroalgae. Biofouling. 18: 205-215
• 2001:
  • C HELLIO et al. Marine antifoulants from brown algae. Biofouling. 17: 189-201
  • C HELLIO et al. Inhibition of marine bacteria by extracts of macroalgae : potential use for environmentally friendly antifouling paints. Mar. Environ. Res. 52: 231-247
• 2000:
  • C HELLIO et al. Phenoloxidase from Mytilus edulis byssus gland: purification, partial characterization and application for screening products with potential antifouling activities. Biofouling. 16: 235-244
  • C HELLIO et al. Inhibition of the development of microorganisms by extracts of marine algae from Brittany (France). Appl. Microbiol. Biotechnol. 54: 543-549
• 1999:
  • C HELLIO, Y LE GAL. Histidase from the unicellular alga Dunaliella tertiolecta : purification and partial characterization. Eur. J. Phycol. 34: 71-78
• 1998:
  • C HELLIO, Y LE GAL. Histidine utilization by the unicellular alga Dunaliella tertiolecta. Comp. Biochem. Physiol. 119A, 4: 753-758

Presentation of results at International Conferences

• 2009
  • Marine Biotechnologies in the marine value chain. Concarneau (France)
• 2008
  • IWA World Water Congress and Exhibition. Montpellier (France)
  • IWA World Water Congress and Exhibition. Vienna (Austria)
  • 3rd Congress of the International Society for Applied Phycology and the 11th International Conference on Applied Phycology. Galway (Ireland)
  • 14th International Congress on Marine Biofouling and Corrosion. Kobe (Japan)
• 2007
  • 5th European Conference on Marine Natural Products. Ischia (Italy)
  • 4th European phycological congress in Oviedo (Spain). 2007
  • 12th International Symposium on Marine Natural Products Queenstown, (New-Zealand).2007
  • 21th International Seaweed Symposium, Kobe (Japan). 2007
  • Meeting of the French Society of Chemistry, Avignon (France). 2007
  • Meeting of the French and Italian Societies of Chemistry, Torino (Italy). 2007
• 2006
  • 13th International Congress on Marine Biofouling and Corrosion. Rio de Janeiro (Brazil). 2006
• 2005
  • 6th Biofouling, Benthic Ecology and Corrosion Meeting. Arraial do Cabo. (Brazil)
  • 4th European Conference on Marine Natural Products. Paris (France)
  • French National Meetng on Biofilm. Lorient (France)
  • Workshop on Marine Antifouling Paints for Navy Ships. Toulon (France)
• 2004
  • Meeting of the British Phycological Society. Lancaster (UK)
  • Annual Main Meeting of the Society for Experimental Biology. Edinburgh (UK)
  • 12th International Congress on Marine Corrosion and Biofouling. Southampton (UK)
  • International Symposium: CSSD “Cyanobacteria for Health, Science and Development, Les Embiez (Six-Fours), France
  • 6th International Symposium of Marine Natural Products. Sorrenteno (Italy)
• 2003
  • Meeting of Office of Naval Research, Baltimore. (US)
  • 3rd european phycological congress. Belfast (UK)
  • Symposium of Chemistry and Biology of Marine Organisms. Chania (Greece)
• 2002
  • European Meeting on Marine Biotechnology. Nantes (France)
  • 3rd European Conference on Marine Natural products. Munich (Germany)
  • International Meeting on Marine Science and Technology for Environmental Sustainability. Newcastle (UK)
  • 11th International Congress on Marine Biofouling and Corrosion. San Diego (US)
• 2001
  • Marine Bioactive Natural Products. Allonissos (Greece)
  • Commission Internationale pour l’Exploration Scientifique de la Mer. (Monaco)
• 2000
  • Microbiology meeting in Finistere. Quimper (France)
  • Natural product from the plants and marine organisms of the mediterranean and atlantic seabord. Lisbon (Portugal)
  • International Marine Biotechnology Congress. Townsville (Australia)
• 1999
  • 2nd Euroconfrence on Marine Natural Products. Santiago de Compostela (Spain)
  • 10th International Symposium of Marine Biofouling. Plymouth (UK)
• 1997
  • International Conference for Marine Microorganisms for Industry, Brest (France)
• 1996
  • Meeting of the Photosynthetics Microorganisms Research Group, Paris (France)

Teaching

• Aquatic microbiology
• Marine pharmacology
• Phycology
• Biotechnology

Supervision of Research projects

Postdocs

• Dr C BULBOA, University of Coquimbo (Chili), epiphytism of commercial macroalgae (2008)
• Dr L BORGES, University of Portsmouth, Development of a chemical-free water treatment system through integrating fibre filters, ultrasound and UV-C (2008)
• Dr D VICENTE, University of Portsmouth, Development of a chemical-free water treatment system through integrating fibre filters, ultrasound and UV-C (2007)

PhD students

• M THABARD, Chemical ecology of Sargassacea species of Martinique Coast
• Z SADDIQUE, Natural products from medicinal plants from Pakistan

PhD students (Collaborative program)

• R JELLALI, PhD University of Maine, Le Mans, France. Evaluation of the in vitro and vivo antifouling properties of new soft coatings composed of modified hydroxytelechelic oligoisoprenes photoreticulation under UV irradiation
• R CHATTER, PhD, University of Tunis, Tunisia. Screening and purification of extracts from Mediterranean brown algae
• E PLOUGUERNE, PhD, University of Western Brittany, France. Screening of marine natural products for antimicrobial activities
• L CHAMBERS, University of Southampton. Evaluation of antifoulings activities of algal extracts

Research assistant

• S STANTON , University of Portsmouth, Development of a chemical-free water treatment system through integrating fibre filters, ultrasound and UV-C
• R MANIBAL, University of Portsmouth, Development of a chemical-free water treatment system through integrating fibre filters, ultrasound and UV-C
• R ARMSTRONG, University of Portsmouth, Development of a chemical-free water treatment system through integrating fibre filters, ultrasound and UV-C Master students
  • A TALL, University of Paris 6, France (2009): Development of new antifouling strategies without chemicals
  • B KIENTZ, University of Nantes, France (2009): Development of a standardised protocol for elimination of microorganisms from algae surfaces
  • A LANEYRIE, University of Lyon, France (2009): Chemical defenses about tropical Sargassum
  • G QUESSEVEUR: University of Paris Sud (2009): Screening of new natural products for potential pharmaceutical bioactivities
  • Y RATRIMOHARINOSY: University of Caen (2008): Screening of new natural products for antimicrobial activities
  • Z ENNARA, University of Lyon, France (2008): Development of a chemical-free water treatment system through integrating fibre filters, ultrasound and UV-C.
  • L BOXHOORN, University of Wanegingen, Netherlands (2008): Development of a chemical-free water treatment system through integrating fibre filters, ultrasound and UV-C.
  • M THABARD, University of Brest, France (2007): Screening of biological activities of extracts of Ralfsia verrucosa, Petalonia fascia and Scytosiphon lomentaria for potential antifouling application.
  • K LEBRET, EPHE, Paris, France (2006-2008): Development of a chemical-free water treatment system through integrating fibre filters, ultrasound and UV-C.
  • C LAGALICE, University of Portsmouth (2006-2008): Studies on the marine fouling alga Ulothrix flacca
  • O BERTRAND, EPHE, Paris, France (2006): Natural compounds from marine microalgae
  • G MIREDIN, EPHE, Paris, France (2005-2006): Study of algal population of Martinique (West-Indies).
  • A PAVITRIN, EPHE, Paris, France (2003-2005): Screening of marine natural compounds for anti-settlement and antimicrobial activities.
  • R TREPOS, EPHE, Paris, France (2003-2005): Chemical communication between microalgal biofilm and larvae of Balanus amphitrite
  • AG JACQUIN, National Museum of Natural History, Paris, France (2003): Research on new non-toxic marine natural compounds with antifouling activities
  • M SEBIRE, EPHE, Paris, France (2002-2004): Chemical communication between bacterial biofilm and larvae of Balanus amphitrite
  • K DEKINDT, University of Lille, France (2001): Endocrinology of larval settlement
  Undergraduate project students
  • 2008-2009
    • E GOULDING: Eutrophication and its impact on coral reef communities changes
    • K MASON: Antimicrofouling activities of new marine natural products from tropical seaweeds
    • C HUGHES: Research of new antibiotics compounds from natural compounds extracted from Pakistanese medicinal plants
    • C JONES: Research of new antibiotics compounds from natural compounds extracted from Pakistanese medicinal plants
    • A CRISTOU: Analysis if ichtyofauna in terms of isotope composition to investigate the role of Posidonia oceanica as a food source in a coastal lagoon
  • 2007-2008
    • G SURU: Isolation, Identification and cultivation of marine microorganisms (bacteria, fungi and microalgae) involved in biofouling of various man-made marine structure (wood, metal, plastic)
    • M BOND: antifouling activities of marine naturals products
    • R PALMER: Chlordecone contamination of Martinique soils and waters: implication on environment and human health
    • H GORDON-BROWN: Microalgae as a source of new natural products
    • M HULL: Impact of global warming on the diversity of microalgae in European waters, and the frequency of toxic blooms.
    • P MARCHAL: antifouling activities of marine naturals products
    • M VANACKER: New environmentally friendly technologies available for the marine engineering sector
  • 2006-2007
    • R IDAOUD, University of Paris 6, France: Screening of biological activities of extracts of Ralfsia verrucosa, Petalonia fascia and Scytosiphon lomentaria for potential antifouling application
    • S OLIVER: The antimicrobial effects of compounds isolated from five species of algae and the soft coral Pseudopterogorgia rigida
    • R ARMSTRONG: An investigation into the antifouling potential of compounds extracted from the brown alga Cystoseira and various marine sponge species
    • N WYATT: An investigation into the use of physical mechanisms to reduce freshwater microalgae
    • S DEIGHTON: An investigation into the antibacterial activities of natural products derived from Cystoseira baccata and Cystoseira tamariscifolia
    • J SILVENT: The antibacterial and antifungal effects of different types of Euphorbia