Pharmacy and Biomedical Sciences

Profile

Qualifications

• BSc
• PhD
• PG Cert.Ed

Internal memberships / posts

• Unit Coordinator
• Induction Tutor (PHBM)
• Year 2 Tutor (BSc Pharmacology)
• Facilitator for inter-professional learning

External memberships

• Fellow of the Higher Education Academy (FHEA)

Key teaching responsibilities

• Year 1: Introduction to cardiovascular system, renal system & blood
• Year 2: Physiology and pharmacology of renal & cardiovascular systems, autacoids, lipids & diabetes mellitus pathophysiology & therapeutics
• Year 3/4: Undergraduate project supervision

Key research interests

Oxidative stress, endothelial dysfunction, cardiovascular disease, diabetes mellitus, cystic fibrosis, copper aminoglycosides, antioxidants, organ preservation;
Supervisor for postgraduate students at PhD and MD level;
Clinical collaboration with Portsmouth Hospitals NHS Trust in diabetes (The Portsmouth Dysglycaemia, Oxidative Stress and the Vascular Endothelium (DOVE) Project).

Recent Publications

More recent publications

Publications before 2006

Laight DW, Therapeutic approaches to organ preservation injury, Expert Opin. Ther. Patents, in press 2005.

Fayers K, Cummings MH, Shaw KM & Laight DW, Nitrate tolerance and the links with endothelial dysfunction and oxidative stress, Br. J. Clin. Pharmacol., 56, 620-628, 2003.

Wotherspoon F, Laight DW, Shaw KM & Cummings MH, Homocysteine, endothelial dysfunction and oxidative stress in type 1 diabetes mellitus, Br. J. Diabetes Vasc. Dis., 3, 334-340, 2003.

Laight DW, Therapeutic approaches to the management of dysmetabolic cardiovascular disease. Expert Opin. Ther. Patents, 12, 615-620, 2002.

Laight DW, Desai KM, Anggard EE & Carrier MJ, Endothelial dysfunction accompanies a pro-oxidant, pro-diabetic challenge in the insulin resistant obese Zucker rat in vivo, Eur. J. Pharmacol., 402, 95-99 2000.