Pharmacy and Biomedical Sciences
Dr James Brown
Principal Lecturer
Pharmacy and Biomedical Sciences
Division of Pharmacology
School of Pharmacy and Biomedical Sciences
University of Portsmouth
St Michael's Building
White Swan Road
Portsmouth
PO1 2DT
Profile
Qualifications
BSc, PhD
Internal memberships / posts
Course Leader of BSc (Hons) Pharmacology
Chair of Board of Studies
Chair of Pharmacology Cognate Area Coursework/Exam Approval Committee
Chair of School of Pharmacy and BMS Course Leaders Committee
Science Faculty Board
School of Pharmacy and BMS Executive Committee
Deputy Licensee for Home Office Pharmacology Teaching Licence
School representative for IPLU1 Committee
AUT representative for HERA implementation (Member of UNCC and ARCIG)
Facilitator for inter-professional learning
External memberships / posts
British Pharmacological Society
RPSGB Academic Pharmacy Group
Key teaching responsibilities
Level 1: Introductory pharmacokinetics and pharmacodynamics and communication skills.
Level 2: Drug development, physiology and pathology of nitric oxide, PAF and endothelin, gastrointestinal physiology and pharmacology, health ethics in relation to clinical trials.
Level 3: Statistics, NO in glutamate mediated cytotoxicity & MED, PCR, Ca/NO measurements & in vivo blood pressure measurements.
Key research interests
Intracellular regulation of NO production; the role of dystrophin/NO in IBD.
Postgraduate students currently supervised, 3 PhD.
Recent Publications
More recent publications
Earlier publications
Yeung D, Zablocki K, Lien CF, Jiang T, Arkle S, Bruthowski W, Brown JF, Lochmuller H, Simmon J, Barnard E & Gorecki DC, Increased muscle cell susceptibility to ATP via alteration of P2X receptor function in the mdx dystrophic mouse, FASBE J, in press 2005.
Francis M, Arkle M, Martin L, Butler TM, Cruz MC, Opare-Aryee G, Dacke CG & Brown, JF, Relaxant effects of parathyroid hormone and parathyroid hormone-related peptides on oviduct motility in birds and mammals: possible role of nitric oxide, General and Comparative Endocrinology, 133, 243-251, 2002.
Tepperman, BL, Soper BD, Chang Q, Brown JF & Wakulich CA, The effect of protein kinase C activation on colonic epithelial cellular integrity. Eur. J. Pharmacol., 389, 131-140, 2000.