Funded PhD opportunities

4D microCT evaluation and digital volume correlation (DVC) of Mg-based alloys for bone regeneration

  • Application end date: 31st December 2017
  • Funding Availability: Funded PhD project (EU/UK students only)
  • Department: School of Engineering
  • PhD Supervisor: Prof Gordon Blunn, Prof Frank Witte (Charite’), Dr Mike Barbeck (Botiss Biomaterials)

Start date: 1 February 2018

Application deadline:  31 December 2017

Interview date: w/c 15th January 2018

Research project code:  ENGN3861217 (Please quote this code in your application form when asked for a research proposal)

Project description 

Applications are invited for a fully-funded, three-year PhD studentship at the University of Portsmouth, to commence at the beginning of February, 2018. This PhD is in collaboration with Botiss Biomaterials and the successful applicant will get the opportunity to work as part of a multi-disciplinary team that brings together expertise in biomaterials for bone tissue regeneration, X-ray computed tomography (XCT), in situ mechanical testing and digital volume correlation (DVC). The candidate will benefit from support in Biomechanical Imaging available at the Zeiss Global Centre (ZGC) in the School of Engineering. Professor Gordon Blunn (University of Portsmouth) and Dr Mike Barbeck (Botiss Biomaterials) complete the supervisory team. 

Project 
Mg-based biomaterlals are able to provide structural support in load-bearing regions and allow bone regeneration to take place over time. However, uncontrolled degradation rate in vivo could result in insufficient mechanical stability during regeneration. Recently, high-resolution microCT imaging combined with in situ mechanical testing (4D evaluation) and digital volume correlation (DVC) allowed a detailed assessment of local microdamage progression, as well as the quantification of 3D deformation in bone-biomaterial systems. However, to date the mechanical competence of Mg-bone integration in vivo is still unknown. The aim of this project is to investigate how the mechanical behaviour of Mg-based implants is influenced by dissolution time and osteoregeneratlon performance. The project will ultimately produce fundamental knowledge aiming at fully establishing Mg-based alloys in the clinical context, through the development of a new generation of products for orthopaedic applications. 

Supervisor profiles

Explore supervisor research profiles, publications and activities on the Portsmouth Research Portal:

Dr Gianluca Tozzi, Senior Lecturer.

Professor Gordon Blunn, Theme Professor (Health and Wellbeing).

Admissions criteria

You’ll need a good first degree from an internationally recognised university (depending upon chosen course, minimum second class or equivalent) or a Master’s degree in an appropriate subject. Exceptionally, equivalent professional experience and/or qualifications will be considered. English language proficiency at a minimum of IELTS band 6.5 with no component score below 6.0. 

Candidate specification 
Applications from candidates with a background in biomechanics, biomaterials, X-ray tomography, mechanical testing or related subject areas are welcomed. The successful applicant will receive adequate training and support to develop the necessary skills for a successful completion of the programme. We are seeking to appoint an enthusiastic and committed candidate with excellent interpersonal and organisational skills. 

Enquiries

Informal enquiries are encouraged and can be made to Dr Gianluca Tozzi on +44 (0)23 9284 2514 or via email at gianluca.tozzi@port.ac.uk.

For administrative and admissions enquiries please contact tech-enquiries@port.ac.uk

How to apply

You can apply online at www.port.ac.uk/applyonline.  You are required to create an account which gives you the flexibility to save the form, log out and return to it at any time convenient to you.

A link to the online application form and comprehensive guidance notes can be found at www.port.ac.uk/pgapply

Funding notes

The fully-funded full-time studentship provides three years of support to cover tuition fees, and a stipend that is in line with that offered by Research Councils UK of £14,553 per annum.