Institute of Biomedical and Biomolecular Science (IBBS)
Biomolecular structure
Head of Division: Professor Geoff Kneale
This section is particularly interested in the structure of, and interactions between, proteins and nucleic acids.
Current projects involve the structural and biochemical investigation of DNA methyltransferases, transcription factors, RNA and DNA binding proteins and other proteins involved in the regulation of gene expression.
A range of biochemical, biophysical and molecular biological techniques are employed to investigate both structural and functional aspects of nucleic acid - protein interactions.
State-of-the-art biophysical facilities include an X-ray Diffractometer with Cryojet (Oxford Diffraction), a Cartesian crystallisation robot, a 600MHz NMR spectrometer with cryo-probe (Varian), Analytical Ultracentrifugation (Beckman XL-A), Surface Plasmon Resonance (BiaCoreT100), Circular Dichroism and Fluorescence Spectroscopy, Laser Light Scattering, and Calorimetry (ITC and DSC). This is complemented by extensive facilities for bacterial growth and protein purification.
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Name
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Position
|
Email
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|---|---|---|
| Prof. Geoff Kneale | Professor of Biomolecular Science | geoff.kneale@port.ac.uk |
| Dr. Darren Gowers | Senior Lecturer | darren.gowers@port.ac.uk |
| Dr. Andy Pickford | Senior Lecturer | andy.pickford@port.ac.uk |
| Dr. Anastasia Callaghan | Senior Research Fellow | anastasia.callaghan@port.ac.uk |
| Dr. John McGeehan | RCUK Academic Fellow | john.mcgeehan@port.ac.uk |
| Dr. Chris Read | Senior Research Fellow | chris.read@port.ac.uk |
| Dr. Pete Cary | Research Fellow | peter.cary@port.ac.uk |
| Dr. Garry Scarlett | Senior Lecturer (joint with Genes and Development) | garry.scarlett@port.ac.uk |
| Prof. Colyn Crane-Robinson | Emeritus Professor | colyn.crane-robinson@port.ac.uk |
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Name
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Position
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Email
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|---|---|---|
| Dr Mikhail Shevtsov | BBSRC postdoc | misha.shevtsov@port.ac.uk |
| Dr. Anna Swiderska | Senior Research Technician | anna.swiderska@port.ac.uk |
| Dr Helen Vincent | Research Fellow | helen.vincent@port.ac.uk |
| Dr. Sarah Thresh | BBSRC postdoc | sarah.brickwood@port.ac.uk |
| Dr Stephen Prior | BBSRC postdoc | stephen.prior@port.ac.uk |
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Name
|
Position
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Email
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|---|---|---|
| Ms Charlotte Henderson | Research Student | charlotte.henderson@port.ac.uk |
| Mr Neil Ball | Research Student | neil.ball@port.ac.uk |
| Ms Claire Fraser | Research Student | claire.fraser@port.ac.uk |
| Ms Louise Butt | Research Student | louise.butt@port.ac.uk |
| Mr Richard Martin | Research Student | richard.martin@port.ac.uk |
| Mr Jack Philips | Research Student | jack.philips@port.ac.uk |