Institute of Biomedical and Biomolecular Science (IBBS)

University of Portsmouth Imaging Centre (UPIC)

Research Groups

Staff Group website Project info
Prof Geoff Pilkington Cellular and Molecular Neuro-Oncology Group Live cell imaging of cancer cells to study motility, invasion and effects of chemotherapeutic agents.
Prof Darek Gorecki Molecular Medicine Confocal imaging for investigating pathogenesis of Duchenne muscular dystrophy, role of dystrophin complex in brain, gene therapy using non-viral vectors.
Prof Arthur Butt Cellular Neurophysiology Fluorescence imaging of glial cells; study of myelination.
Dr Keith Firman Bionanotechnology DNA manipulating enzymes that constitute a single molecule nanoactuator, studies of which involve AFM imaging of single molecules (DNA and DNA-binding enzymes) and measurement of forces of interaction within the system.

Dr John Tsibouklis

Dr Eugen Barbu

Dr Dimitrios Fatouros

Dr Marta Roldo

Dr James Smith

Bioadhesion and Drug Delivery Group Use of AFM to determine surface energy, an important parameter in the study of bioadhesion. AFM has also been used to image single walled carbon nanotubes for drug delivery in nanomedicine.
Dr Jan Shute Cystic Fibrosis Asthma Various microscopy techniques used to investigate tissue damage and repair and for characterising novel mucolytics.
Dr Sassan Hafizi Cellular Signalling Wound-healing assays using live cell imaging.

Dr James Smith

  STM and AFM imaging of proteins: Immobilisation and tunnelling mechanisms in proteins such as reverse transcriptase is a collaborative venture with Helmholtz Zentrum Berlin.