Institute of Biomedical and Biomolecular Science (IBBS)

Major Research grants

Externally funded research grants of over £10m have been awarded to researchers in the Institute of Biomedical and Biomolecular Science in recent years, as listed below.

2012

  • Biophysical and physiological characterisation of potassium channels from pathogenic fungi. £392,000 to Dr Tony Lewis (BBSRC), 2012-2015
  • Chemical and Physical Compatibility of Continuous Intravenous Drug Infusion Combinations Used In Paediatric Intensive Care. £41000 to Dr Marisa van der Merwe (PI) and Dr Karen Ball in collaboration with University Hospital Southampton NHS Foundation Trust  (Neonatal and Paediatric Pharmacy Group) 2011-2012

2011

  • The European Xenopus Resource Centre. £454,500 to Prof. Matt Guille and Dr Colin Sharpe (Wellcome Trust) 2011-2013
  • Developing a novel array technology, £152,000 to Dr Anastasia Callaghan (BBSRC) 2011 - 2012

2010

  • Comparative analysis of the initial nerve connections in the embryonic vertebrate brain. £58,000 (Anatomical Society) 2007-2010 
  • Innovative techniques and models to study Glia-Neuron interactions. £159,579 to Prof Arthur Butt (EU, Marie Curie Scheme, EdU – GLIA) 2010-2013
  • DNA Distortion, Sequence Recognition and the Control of R-M Gene Expression. £445,031 to Prof Geoff Kneale and Dr John McGeehan (BBSRC) 2010-2013

2009 

  • Research Design Service South Central RDSSC. £916,050 to Prof. Tara Dean (Dept of Health National Institute of Health Research) 2009-2013
  • Portsmouth Adult Alcohol Misuse Needs Assessment Study. £28,228 to Prof Tara Dean and Saseendran Pallikadavath (Portsmouth City Council) 2009
  • An in-depth investigation of Food Hypersensitivity in older children. £334,270 to Dr Carina Venter and Prof Tara Dean (National Institute of Health Research) 2009-2013
  • Molecular Machines that use structured DNA for directed movement. £309,160 to Dr Keith Firman and Dr James Youell (EPSRC via NanoSci-E+) 2009-2012
  • The Tensin phosphatase family: their biological functions and roles in human diseases. £42,000 to Dr Sassan Hafizi (Swedish Research Council) 2009-2010
  • Critical role for the inwardly rectifying potassium channel Kir4.1 in astrocyte and oligodendrocyte functions. £346, 500 to Prof Arthur Butt (Medical Research Council) 2009-2012
  • Molecular Biology of Brain Tumour Invasion: the role of CD155 and CD44. £60,000 to Prof Geoff Pilkington (Brains trust and Brain Tumour UK) 2009-2010
  • VCSRNAHV – Investigating sRNAs as the master on/off switch of Vibrio Cholera virulence. £35,714 to Dr Helen Vincent (European Commission) 2009-2011

2008

  • Development of a human 3D in vitro model of the blood-brain barrier. £51,300 to Prof. Geoff Pilkington (The Lord Dowding Fund) 2008 - 2009
  • Nanoparticulate chemotherapeutic drug transporters for delivery across the blood brain barrier. £451,314 to Dr Eugen Barbu, Dr John Tsibouklis, Prof. Geoff Pilkington and Prof. Darek Gorecki. (BBSRC) 2008-2011
  • The interplay of sRNAs, Hfq and RNase E in the control of gene expression. £340,000 to Dr Anastasia Callaghan (BBSRC) 2008-2011

2007

  • Water Softeners for Atopic Eczema: Randomised controlled trial of ion-exchange water softeners for the treatment of atopic eczema in children. £981,179 to Dr H. Williams and Prof. Tara Dean (Department of Health). 2007-2009
  • GD3 in paediatric brain tumours. £82,000 to Prof. Geoff Pilkington, Prof Arthur Butt & Dr Darek Gorecki. (Ali’s Dream/Charlie’s Challenge) 2007-2010
  • Cancer stem cells in paediatric brain tumours. £86,000 to Prof. Geoff Pilkington. (Ali’s Dream/Charlie’s Challenge) 2007-2010
  • Protein structure determination from nuclear magnetic resonance (NMR) spectroscopy using swarm intelligence. £296,000 to Dr Andrew Pickford (BBSRC) 2007-2010
  • Structural biology of type 1 restriction-modification enzymes. £195,120 to Prof. Geoff Kneale (Wellcome Trust) 2007 – 2010
  • Computer imaging for identification of Xenopus. £59,194 To Dr Matt Guille ( NC3R'S) 2007-2008

2006

  • A European Stock Centre for Xenopus. £1,472,290 to Dr Matt Guille (Wellcome Trust) 2006-2011
  • Structural analysis of the genetic switch controlling expression of the AhdI restriction-modification system. £484,590 to Prof. Geoff Kneale (BBSRC) 2006-2010
  • BioNano-Switch: A Biological Nanoactuator as a Molecular Switch for Biosensing. £278,321 to Dr. Keith Firman (European Commission) 2006-2009
  • Location of DNA target sites by proteins and nucleic acids. £208,910 to Dr Darren Gowers (BBSRC) 2006-2009
  • Function and expression of purinioceptors in white matter astrocytes in situ. £289,902 to Prof. Arthur Butt (BBSRC) 2006-2009
  • ParaShift. £86,345.00 to Prof. Martin Ford (BBSRC) 2006-2007
  • The influence of different dynamic cooling profiles on the regional and whole body perception of thermal comfort. £60,676 to Prof. M. Tipton (WL Gore) 2006-2009

2005

  • Development of a validated Quality of Life scale for children and young people with speech and language difficulties. £195,000 to Chris Markham and Prof. Tara Dean (Department of Health) 2005-2008
  • Development of a 3D “all human” in vitro model for the study of brain tumour invasion.  £211,000 to Prof. Geoff Pilkington (Dr Hadwen Trust ) 2005- 2008
  • Deuteration Initiative for Biological Neutron Scattering and NMR. £800,000 to Prof. Geoff Kneale and UK collaborators. (EPSRC) 2005-2008
  • Fibroblast growth factor 2 receptor signalling mechanisms in Demyelination and remyelination. £81,043 to Prof. Arthur Butt (Multiple Sclerosis Society) 2005-2008
  • NG2 Ablation in monolayer and spheroid confrontation cultures of paediatric brain tumours: biological consequences and therapeutic possibilities. £75,000 to Prof. Geoff Pilkington (Ali's Dream) 2005-2008

Previous Grants