star Research Students

The following Postgraduate Research Students have completed their doctorate during the REF census period. For a list of current students please view departmental pages. Where possible, we have linked to the full-text electronic version of the PhD theses. The other PhD theses are available on request by contacting elibrary@port.ac.uk.

Name Project Title
BURKI, Umar Abdullah The Effects of 5-HT1A Receptor Agonists on Food Intake in Rodents: A Novel in vivo Animal Model to Assess Psychoactive Compounds for Potential Antidepressant Activity
CLARKE, Sarah Louise Targeting Intracellular Neutrophil Elastase in the Treatment of Airway Inflammation in Cystic Fibrosis
DELVES, George Henry Investigation into the Characteristics and Properties of Prostasomes
ELGASS, Simone An Investigation into the Biological Effects of Lycopene at Cellular and Molecular Level
HANLON, Timothy Robert George British Army Doctors' Views on Medicines Management (Prescribing and Dispensing)
HEALE, Graham Stanley CPD and Practice Change: The Chiropractors' Perspective
HIGGINS, Samantha Caroline The NG2 Chondroitin Sulphate Proteoglycan: A Possible Target for Malignant Glioma?
LEONI, Giampaolo Characterisation of NG2-Glia and an Immunoablation Approach to Study their Functions in the C.N.S.
LLEWELLYN, Katrina Jean The Role of an A-Form DNA Element in Transcriptional Regulation of the Xenopus gata2 Gene
MILLER, Peter John Attitudes and Opinions of Chiropractic Teaching Staff Towards Methods of Detecting the Spinal Manipulable Lesion
MOLNAR, Eva Modified-Chitosan Nanoparticles for Drug Delivery through the Blood-Brain Barrier
MOORHEAD, Jane Diane Differential cellular kinetics and survival features of the main types of malignancy by patient age
STEPHENS, Jonathan Paul The Pharmacology of Non-Freezing Cold Injury in the Rat Tail Vascular Bed in vitro
TROLLOPE, Alexandra Fay The Role of the Linker Histones in Early Chicken Development
WIGLEY, Rebekah Josephine NG2-Glia: A Synaptic Element with Neural Stem Cell Potential
WILTSHIRE, John Howard An in vitro and in vivo Analysis of Retinoid Receptor-Nucleosome Interactions and Chromatin Remodelling
AL-BRAIK, Fatima Ali Usage and Safety of Herbal Medicines in Patients Attending Primary and Secondary Care Clinics in Abu Dhabi, UAE
AMAR, Sabrina Histone Modification and its Role in Epigenetic Regulation
ARNOLD, Laurence Henry Biophysical Characterisation of Collagen Binding by the Hemopexin Domain of Matrix Metalloproteinase-1 (MMP-1)
AZIM, Kasum Kinase Signalling in Cells of the Oligodendrocyte Lineage
BAY, Virginia Elisabeth Expression and Function of Inward Rectifying Potassium Channels in CNS Glia
DAVIS, Zadie Alethea Immunoglobulin Heavy Chain Variable Region Gene Analysis in Chronic Lymphocytic Leukaemia
DONOVAN, Laura Kate CD133, the Holy Grail of Neuro-Oncology, or a Promiscuous Red-Herring?
ELDERDERY, Abozer Yousif Ahmed The Prevalence of Haemoglobin Variants in a Sudanese Population: Haematological and Molecular Analysis
ENGLAND, Edward John How Patients with Osteoporosis Understand the Local Decision Making Process for Medicines and Guidelines
FRY, Kathryn Emily Development of a Three-Dimensional, all-Human in vitro Model of the Blood-Brain Barrier for Cancer Metastasis Studies
LAMPROU, Dimitrios Towards the Determination of Surface Energy at the Nanoscale
LARKIN, Samantha Elizabeth Thornton Molecular Characterisation of Prostate Cancer Progression Markers
MACGREGOR, Helen Jane The Pro-Inflammatory Role of Copper in Chemokine Multimerisation and the Potential of Copper Chelators as Anti-Inflammatory Agents
MURRAY, Samantha Angel Significance of Serum Supplementation Type on Gene and Protein Expression in Human Glioma Cells in vitro
SMITH, Jason James Development of Improved Chemotherapy and Maintenance Therapy for Metastatic Cutaneous Melanoma
AGHIGHI, Saman Global coagulation assays in haemophilia: comparison and correlation with conventional assays and clinical phenotype (Doctor of Biomedical Sciences)
AL RUWAILI, Jamal Al Hameedi Serum Proteomic Analysis of Prostate Cancer Progression
BIRKS, Suzanne Mary GD3 as a Potential Therapeutic Target in Glioma
FORDHAM, Daniel George Development of a biosensor using aptamer/antigen interactions
HARVEY, John Contribution of molecular testing histocompatability in improving haematopoietic stem cell transplant outcomes
HERRERA GARCIA, Luisa Helena Evaluation of a foundation degree for pharmacy technicians
LI, Yanhong A study of the incorporation of antischistosomiasis drugs into polyheterocycles and DFT calculations on polymer precursors
MAHERALLY, Zaynah Receptors for hyaluronic acid and poliovirus: expression and role in glioma invasion
MAKAMA, Zakari Cathodic delamination of modelled sea cable connector assemblies
NEWMAN, Emily Rebekah Biophysical analysis of the Nucleosome Assembly Protein and its interaction with histones
PAGE, Suzannah Jayne The expression of Hex, fli1 and Tal1 proteins in Xenopus embryos
PEREGRIN, Katharine Anne Sensitivity to and functional effects of tricyclic agents on glioma: an immunohistochemical and in vitro study
RENNISON, Susan Mary Student engagement with formal lectures on the MPharm programme at the University of Portsmouth
SAMUEL, Carol Ann An investigation into the efficacy of reflexology on acute pain in healthy human subjects
SIKORA, Aneta Elzbieta Structure-function analysis of a multifunctional enzyme using the atomic force microscope
TANG, Soumi Amy Evaluating the Evidence Base in Pharmacovigilance Decision Making
WARE, Michelle Ann Analysis of the initial nerve connections in the embryonic vertebrate brain
YOUNG, Christopher Nicholas James Abnormalities in P2X7 receptor expression and function in muscle of the mdx mouse model of Duchenne Muscular Dystrophy
ATKIN, Marc The effects of garlic upon endothelial function, vascular inflammation, oxidative stress and insulin resistance in patients with type 2 diabetes at high cardiovascular risk: a double blind randomised placebo controlled trial
BALL, Neil James Structural and functional characterisation of the interaction of the gene regulatory protein C.Esp1396I with its DNA recognition sites
BLAIN, Joanne Lesley Evaluating the quality of medicines-related information in the electronic discharge summary
GIERYCZ, Marta Investigating copper chelation as an anti-inflammatory strategy in cystic fibrosis
GOODHAND, Isabel Mary A Novel Assay for the Quantification of Active Transcription Factors
HENDERSON, Charlotte Anne The Interplay of sRNAs, Hfq and RNase E in the Control of Gene Expression
HURST, Hugh Charles Outcomes of back and neck pain patients undergoing chiropractic treatment and can these be predicted?
LONGCROFT-WHEATON, Gaius Novel endoscopic techniques in early gastrointestinal neoplasia
NAZAR, Hamde Jamal Preparation and evaluation of a thermosensitive hydrogel for the nasal delivery of insulin
PRICE, Robert Jordan The role of histone variants and hnRNPs in early Xenopus laevis development
THOMAS, Peter Guy Burnout and work engagement levels in community pharmacists residing in three counties of the United Kingdom
TOMLIN, Mark Edward Medication Errors - Capture and Prevention by Pharmacy
ADELUGBA Aderemi The assessment of reticulocyte and erythrocyte haemoglobin contents, and their use in the evaluation of iron status in hospitalised patients
BRASKO Csilla Expression of inward rectifier potassium channel subunits in optic nerve glia
BROWN Katherine Utility of the Calliphora vicina (Diptera: Calliphoridae) pupal stage for providing temporal information for death invesigations
CARTER Jessica Epigenetic basis for Tensin3 dysregulation in human renal cell carcinoma
EVANS Luke Shaun An investigation into novel helicases from Plasmodium falciparum
FRASER Claire Louise Bisubstrate kinetics and processivity measurements on Escherichia coli DNA ligase A
GLAYSHER Sharon Louise Synergistic interactions of targeted therapy within signal transduction pathways
IBRAHIM Youhanna Wiliam Mansour Controversies in the Epidemiology of Infectious Corneal Ulcers and Related Risk Factors
KHAN, Azra The Association of Plasmid-borne qacAB and Antimicrobil Resistance in Meticillin-resistant Staphylococcus aureus: Understanding the Research to Influence Attitudes and Perceptions of Biomedical***
MA Jie Chemical profile of ginseng, Epimedium, Rhodiola and Siberian ginseng extracts and stability of their formulated products
MEAD Robert James Circulating DNA markers of gastro-intestinal cancers
RAGHAVAN Rajeev Prathivadhibhayankaram Aspirin in type 2 diabetes: a survey of prescribing habits and investigation of effects on inflammation, oxidative stress, insulin resistance and endothelial function.
TOMAN Petr Nanoparticles from Alkylglyceryl-modified Polysaccharides for Drug Delivery to the Brain
UPSON Sarah Jane Multifunctional Coatings for Oral Care: Structure-activity Relationships
WHALE John Mitochondrial DNA analysis of four ethnic groups of Afghanistan

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star Research Collaborations

The Institute of Biomedical and Biomolecular Sciences is a multi-disciplinary research Institute, enabling numerous collaborations between researchers, both within and between groups. A major success of the Institute’s research strategy has been to promote new collaborations with the NHS and national and international institutes, which is evidenced by new funding streams, increased quality and quantity of publications, and the enhanced international profile of our researchers. 52% of our submitted publications are international collaborations and a further 24% are with collaborators within the UK.

International Collaborations

  • EXRC partnerships with 96 labs worldwide (Guille)
  • TC2N partnerships with 17 EU labs (Gorecki/Swinny)
  • EduGlia partnerships with 12 EU labs (Butt)
  • University of the Saar, Germany (Butt/Kirchhoff)
  • University of Groningen, The Netherlands (Swinny/ van der Want)
  • Harvard, USA(Swinny/ Rudolph)
  • University of Vienna, Austria (Swinny/ Klausberger/ Sieghart Vienna)
  • Milan, Italy (Shute)
  • Rome, Italy (Shute/Cazzola)
  • Central Leather Research Institute in Chennai (Tsibouklis/ Reddy)
  • 'Gr.T.Popa' University, Romania (Tsibouklis/Verestiuc)
  • Aristotle University of Thessaloniki (Tsibouklis/Fatouros)
  • University of Padua, Italy (Tsibouklis/Calliceti)
  • Florida Atlantic University, USA (Pickford/Fields)
  • Salzberg, Austria (Pilkington/Vlasak)
  • Institut Cochin, Paris, France (Pilkington/Couraud)
  • Weill Medical College, New York, USA (Pilkington/Weksler)
  • Yunnan University, China (Pilkington/Huang)
  • Kunming Medical College, Yunnan, China (Pilkington/Zhao)
  • Institut Laue-Langevin, Grenoble (Kneale/Callow)
  • Institute of Molecular and Cell Biology, Warsaw (Kneale/ Bujnicki)
  • Waksman Institute, Rutgers University, New jersey, USA (Kneale/Severinov)
  • National Prion Disease Pathology Surveillance Center, Case Western Reserve University School of Medicine, Ohio, USA (Kneale/Zou)
  • Leiden University Medical Centre, The Netherlands (McGeehan/Ravelli)
  • NREL, Colorado, USA (McGeehan/Beckham)
  • Institut Cochin, Univ. Paris Descartes, Paris, France (Dietrich/ Maire)
  • University of Utah, USA (Dietrich/ Kardon)
  • University of Campinas, São Paulo, Brazil (Dietrich/ Alvares)
  • Institute of Molecular & Cell Biology, National University of Singapore (Dietrich/Ingham)

National Collaborations

  • The Defence Science and Technology Laboratory (Tsibouklis / Willis)
  • Reading University (Butt / Rattray)
  • Warwick (Butt / Pankratov)
  • Manchester University (Butt/Verkhratsky)
  • King’s College London (Butt/Bradbury)
  • Glasgow University (Butt/Hafizi/Barnett)
  • Dundee University (Swinny/ Lambert)
  • University of Sussex (Swinny/ Stephen)
  • Oxford University (Swinny/Magill/ Lamsa)
  • Liverpool University (Shute)
  • DSTL Porton Down (Shute)
  • Oxford (Pickford/Campell)
  • St Andrews University (Pickford/Schwarz-Linek)
  • King’s College Hospital (Pilkington/Ashkan)
  • Wolverhampton University (Pilkington/Warr)
  • Oxford Brookes (Pilkington/King)
  • Milton Keynes (Pilkington/Romero)
  • Warwick University (Pilkington/Cree)
  • Edinburgh University (Kneale/ Dryden)
  • Leeds University (Kneale/ Trinnick)
  • National Institute for Medical Research (NIMR), Mill Hill, London (Kneale/ Taylor)
  • Sussex University (Kneale/ Caldecott)
  • Cambridge University (Callaghan/ Luisi)
  • Oxford (Callaghan/ Sobott), National Institute for Medical Research, Mill Hill, London (Callaghan/ Driscoll)
  • Diamond Light Source (Callaghan/Malfois)
  • Royal Free / UCL, London (Kolstoe/ Wood/ Pepys)
  • Research Complex at Harwell, RAL (Kolstoe/ Owens)
  • Manchester University (Guille/ Amaya)
  • Kent (Guille/Spencer)
  • ZSL (Guille/Holt/Gardner); NIMR, London (Guille/Smith)
  • Cambridge University (Dietrich/Lewis)
  • East Anglia (Dietrich/Munsterberg); University College London (Dietrich/Tada)
  • King’s College London (Dietrich/Basson).

NHS Collaborations play a key part of the Institute’s strategy for increasing translation of our fundamental research, and major new collaborations include South East Brain Tumour Association/SEBTA (Pilkington - Kings College Hospital, Frenchay Hospital, Bristol, Peninsula College of Medicine & Dentistry & Derriford Hospital, Charing Cross Hospital & Imperial College, Southampton General Hospital and Hurstwood Park Clinical Neurosciences Centre, Sussex), and translational research in respiratory diseases (Shute - Anoop Chauhan, Respiratory Consultant, QAH, and Director of R&D for the Portsmouth University Hospitals Trust; Peter Howarth, Respiratory Consultant, Southampton General Hospital; Alan James, Consultant at Sir Charles Gairdner Hospital, Perth; Gary Connett, Paediatric Respiratory Consultant, Southampton General Hospital) and inflammatory bowel disease (Brown - Pradeep Bhandari, Consultant Gastroenterologist, QAH), and mitochondrial diseases (McGeehan/ An - Keyoumars Ashkan, Consultant Neurosurgeon, King’s College Hospital, London; Prof. Diana Eccles, Director, University of Southampton Clinical Trials Unit).

Industrial Collaborations are also seen as essential for ensuring the relevance of our world-class fundamental research to potential end-users, and the Institute’s work includes collaborations with: Pfizer (Shute/Pickford); Hoffmann La Roche, Switzerland (Swinny); Synova, Tubingen (Pilkington); Healthcare Products, Sussex (Pilkington); Novartis (Tsibouklis); GlaxoSmithKline (Tsibouklis); Novozymes (McGeehan).

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