School of Pharmacy and Biomedical Sciences

Staff

Dr John Tsibouklis

  • Qualifications: BSc, MSc, PhD, CChem, FRSC
  • Role Title: Reader in Polymer Science
  • Address: St Michael's Building, White Swan Road, Portsmouth, PO1 2DT
  • Telephone: 023 9284
  • Email: john.tsibouklis@port.ac.uk
  • Department: School of Pharmacy and Biomedical Sciences
  • Faculty: Faculty of Science

Biography

Biomaterials with inherent resistance to bacterial colonisation, Bioadhesion/mucoadhesion, Surface Science Research, Colonic drug delivery, Ocular drug delivery, Boron neutron-capture therapy.

For more information about my research please visit my lab page

Teaching Responsibilities

Academic Roles:

Board of Institute of Biomedical and Biomolecular Sciences Member, School Research Committee

Teaching:

Level 2:  Chemistry for Pharmacy, Applied Spectroscopy and Analytical Techniques

Research Interests

  • Controlled and targeted drug delivery: design and development of specific retentive delivery systems aimed at mucosal surfaces; nanomaterials for the transport of chemotherapeutant; stimuli-responsive polymer conjugates for the release of therapeutic agents.
  • Low-surface-energy materials: synthesis, surface characterisation of polymeric materials with ultra-low-surface-energy characteristics.
  • Bioadhesion/mucoadhesion: bioadhesive materials for therapeutic use in the eye, mouth, stomach and colon.
  • Biomolecular recognition: receptor molecules with potential applications as either binding agents or controlled release systems; support matrices for in vitro toxicology.
  • Bioadhesion control: development of materials that inhibit bacterial binding to biological surfaces and biomaterials; use of responsive ('smart') polymers displaying hydrophilic-hydrophobic transitions.
  • Therapeutic agents for targeting cancer tumours: boronated cages for cancer therapy; delivery vehicles for the transport of chemotherapeutants across the blood-brain barrier.
  • Surface science research: the use of contact angle goniometry, atomic force microscopy, X-ray photoelectron spectroscopy, infrared spectroscopy and other techniques as means of quantifying surface heterogeneity. 

Publications

View all publications on Parade…

Funding

  • Room Temperature Ionic Liquid Gels, 2013-2015, Î309.000, from 1/10/2013.
  • Polymers for site-specific drug delivery, 2008-2012, Novartis, £217,000, from 1/9/2010.
  • Polymers for oral care, 2008-2012, BBSRC Industrial CASE (GlaxoSmithKline), £100,000, from 1/9/08.
  • Nanoparticulate polymers as chemotherapeutic drug transporters for delivery across the blood brain barrier, 2008 – 2011, funded by the BBSRC, £451,315, from 1/5/08 (PI Dr Barbu). 

Presentations

  • Drug Discovery Congress, Munich (2013)
  • The Future of Drug Delivery Systems, London (2011)
  • Drug Delivery Partnerships Meeting, Brussels (2010)
  • Novartis, Horsham (2010)
  • Kingston University, London (2010)

Collaborations

University of Iasi (Romania), Aristotle University of Technology (Greece), Central Leather Research Institute in Chennai (India), Kingston University (UK), Novartis (UK), GlaxoSmithKline (UK), Defence Science and Technology Laboratory (UK).

Reviewer, expert panel member and/or rapporteur for: National Science Foundation (USA), Expert Panel Member for RTD Programme Monitoring (European Union), Government of Alberta Equipment Grants Program (Canada), Science Foundation (Ireland), National Council for Research and Development (Romania), Research Promotion Foundation (Cyprus), Ministry of Education (Greece), Innovation and Technology Commission (Hong Kong).

Postgraduate Research Supervised

Daniel Ibegbu:  Nanoparticles for brain-specific drug delivery, 2012-2015

Ashley Smith BSc:  Nanoparticles for the therapeutic applications, 2011-2014

Temidayo Ogunosun: Liposomes in the drug delivery of carboranes, 2009-2015

Achievement and Recognition

Member of the International Editorial Advisory Board for the Research Journal “Therapeutic Delivery” (2009)

Member of the Editorial Board of “The Open Biomedical Engineering Journal” (2007)

Military Pharmaceutical Laboratories of the Hellenic Army award for contributions towards the Advancement of the Pharmaceutical Sciences (March 2003)

Visiting Professorship at Chulalongkorn University, Thailand (January 2002)

SCJohnson “Silver Dollar” Award (2001 & 2002)

Memberships

Fellow, Royal Society of Chemistry

RSC Honorary Representative (Mid-Southern Counties)

Member, Analytical Division of the Royal Society of Chemistry

Member, Faraday Division of the Royal Society of Chemistry

Member, Macro Group UK