School of Pharmacy and Biomedical Sciences
Dr Mohsen Seifi
- Qualifications: BSc (Hons) Pharmacology, PhD
- Role Title: Senior Research Associate
- Address: School of Pharmacy and Biomedical Sciences
- Telephone: 023 9284 3572
- Email: email@example.com
- Department: School of Pharmacy and Biomedical Sciences
- Faculty: Science
I completed my undergraduate degree in BSc (Hons) pharmacology at the University of Portsmouth in 2011, which included two individual research studentship awards to work on a research project investigating the localization of NG2 immunoreactive neuroglia cells in the rat locus coeruleus and their plasticity in response to stress.
I then went on to obtain a PhD in the Neurochemical Anatomy & Psychopharmacology Group with Dr Swinny at the University of Portsmouth investigating the expression and function of GABA A Rs within the enteric nervous system of the mouse colon and their plasticity in response to stress and ageing.
Since 2015 I have been a Senior Research Associate working under the supervision of Dr Jerome Swinny. My current project is focussed on characterisation of Alzheimer’s disease induced alterations in native enteric nervous system and gastrointestinal function in a mousemodel of Alzheimer’s disease. This project is funded by Alzheimer’s Research UK (ARUK) and involves a range of experimental techniques, including molecular biology (Immunohistochemistry, Confocal microscopy, qPCR, Western Blotting and Elisa) and electrophysiology and pharmacology (Organ bath preparations, in vitro and in vivo motility assays).
I currently deliver lectures on the following units:
- Cells to Systems, Function and Histology of the Gastrointestinal System (Level 4 Biomedical Science, MPharm and Pharmacology students)
- Introduction to Neuroscience and Pharmacology, Anatomy and Function of the Autonomic Nervous System (Level 4 Biomedical Science, MPharm and Pharmacology students)
- Neuropharmacology Advanced Research Methods in Neurobiology (Level 6 Pharmacology)
I have provided Demonstratorship on the following laboratory classes
- Guinea pig ileum lab classes used as a tool to teach the cholinergic pharmacology.
- Rat aorta and trachea preparations used as a tool to teach the autonomic pharmacology.
- Histology lab classes in which students are introduced to the histology of various organs and tissues using light microscopy and various histological staining methods.
- Enzyme kinetics lab classes used to teach the effect of variable factors such as temperature and PH on enzyme kinetics.
Undergraduate and Postgraduate Research project supervision
- I routinely supervise undergraduate and postgraduate research project students within the School.
Senior Research Associate in the Neurochemical Anatomy & Psychopharmacology Group (Lab page: http://www.port.ac.uk/institute-of-biomedical-and-biomolecular-science/cell-biology-and-pharmacology/jerome-swinny)
Area of focus:
Expression and function of various neurotransmitter/neurotransmitter receptor systems within the peripheral and central nervous systems, in health and disease.
1. The Role of the Brain Locus Coeruleus (LC) Nucleus in PD-induced stress and anxiety.
2. Molecular, functional and histological characterisation of neurotransmitter receptor systems within various peripheral organs.
3. Characterisation of the Alzheimer’s disease induced alterations in the enteric nervous system and gastrointestinal function.