Biography

I am PI in the Brain and Behaviour Lab at Portsmouth, which I established in 2015, and research lead in the Zebrafish Research Facility. In my group we study the basis of compulsive behavioural disorders, and I have published more than 50 peer reviewed articles, chapters and scholarly reviews in this area, encompassing work on compulsive behavoiur in a variety of species, from fish, to farm animals to humans. We carry out basic research using zebrafish as a model species in order to understand the biology of compulsive disorders, concentrating on the interaction between molecular (genetic/epigenetic) and environmental (e.g., alcohol, stress) factors invovled, and the associated neural circuits. Our approach is theoretically guided by the principles of precision medicine, i.e., that understanding the biology of neuropsychiatric conditions will help develop individualised treatments for patients. We also carry out preclinical/translational research in humans, in particular looking at the interactions of impulsivity, risk-taking (personality) and (environmental) stress on alcohol use and misuse.

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