High-Throughput Discovery of Novel Antibiotics
Self-funded PhD students only
School of Pharmacy and Biomedical Sciences
Open all year round
This is a self-funded, 3 year full-time or 6 year part-time PhD studentship, starting in October 2019 or February 2020. The project is supervised by Dr Roger Draheim.
The goal of this PhD project is to implement a biological antibiotic screening platform within our School of Pharmacy and Biomedical Sciences. Your work will help to reduce the cost required for antibiotic discovery, with the ultimate aim of becoming the de facto standard within the pharmaceutical industry.
Antimicrobial resistance (AMR) is becoming a major problem in healthcare, causing complications in the treatment of the diseases caused by many clinical bacterial pathogens. In the European Union alone, antibiotic-resistant infections kill nearly 25,000 patients and costs £1.5 billion per year. The Chief Medical Officer (CMO) of the United Kingdom termed antibiotic resistance “a major area of concern”, and proposed its inclusion on the National Security Risk Assessment, which priorities major threats to national security.
The work will include:
- training and experience across biological science disciplines, including: molecular biology, microbiology, biochemistry, high-throughput screening and collection and management of large data sets (i.e. big data).
- access to training resources available from our Graduate School, to improve presentation skills, time-management and project organisation skills, as well as reviewing literature, thesis writing, data analysis, statistics, and more
The CMO suggested that the UK government facilitate global action, especially the development of novel antibiotics. However, the cost of the research, development and clinical testing required to bring an antibiotic to market, coupled with the fact that they are only used for a very short period of time by patients, makes them very unattractive to pharmaceutical companies.
This PhD project addresses this shortfall in research, and tackles this growing problem.
Self-funded PhD students only. PhD full-time and part-time courses are eligible for the Government Doctoral Loan.
Home/EU/CI full-time students: £4,327 p/a*
Home/EU/CI part-time students: £2,164 p/a*
International full-time students: £15,900 p/a*
International part-time students: £7,950 p/a*
Please note: all students must also pay bench fees of £10,000 p/a.
By Publication Fees 2019/2020
Members of staff: £1,610 p/a*
External candidates: £4,327 p/a*
*All fees are subject to annual increase.
- A good honours degree or equivalent in a relevant subject or a master’s degree in an appropriate subject.
- Exceptionally, equivalent professional experience and/or qualifications will be considered. All applicants are subject to interview.
- English language proficiency at a minimum of IELTS band 6.5 with no component score below 6.0.
Make an enquiry
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How to Apply
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Interview date: TBC