Biography
I run the The Dysglycaemia, Oxidative stress and the Vascular Endothelium (DOVE) Project which is a clinical collaboration between myself and the Academic Department of Diabetes and Endocrinology, Queen Alexandra Hospital (Portsmouth Hospitals NHS Trust), that aims to examine the roles and interactions of both traditional and non-traditional metabolic and cardiovascular risk factors in diabetes mellitus.
Research interests
Oxidative stress, endothelial dysfunction, cardiovascular disease, diabetes mellitus, cystic fibrosis, copper aminoglycosides, antioxidants, organ preservation; Supervisor for postgraduate students at PhD and MD level; Clinical collaboration with Portsmouth Hospitals NHS Trust in diabetes (The Portsmouth Dysglycaemia, Oxidative Stress and the Vascular Endothelium (DOVE) Project).
Research outputs
2025
Spatiotemporal diversity in molecular and functional abnormalities in the mdx dystrophic brain
Pomeroy, J., Borczyk, M., Kawalec, M., Hajto, J., Carlson, E., Svärd, S., Verma, S., Bareke, E., Boratyńska-Jasińska, A., Dymkowska, D., Mellado-Ibáñez, A., Laight, D., Zabłocki, K., Occhipinti, A., Majewska, L.,
20 Mar 2025, In: Molecular Medicine. 31, 1, 33p., 108
Research output: Article
2021
A randomised placebo controlled trial of VSL#3® probiotic on biomarkers of cardiovascular risk and liver injury in non-alcoholic fatty liver disease
Chong, P. L., Laight, D., Aspinall, R. J., Higginson, A., Cummings, M. H.
1 Apr 2021, In: BMC Gastroenterology. 21, 1, p. 1-9, 9p., 144
Research output: Article
2020
Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) in human lung microvascular endothelial cells controls oxidative stress, reactive oxygen-mediated cell signaling and inflammatory responses
Khalaf, M., Scott-Ward, T., Causer, A., Saynor, Z., Shepherd, A., Górecki, D., Lewis, A., Laight, D., Shute, J.
29 Jul 2020, In: Frontiers in Physiology. 11, 20p., 879
Research output: Article