

Dr Murphy Wan
Biography
Dr. Murphy Wan is a Senior Lecturer in Biomedical Sciences at the University of Portsmouth's School of Medicine, Pharmacy, and Biomedical Sciences.
Her research focuses on the discovery of novel therapies for human diseases, integrating omics-driven approaches to uncover disease mechanisms and identify biomarkers with translational potential for future clinical applications.
Current Research Areas:
- exploring the potential of natural compounds as novel cancer therapeutics
- developing novel small-molecules in targeting cancer signaling pathways
- investigating the immunological potential of molecules excreted from bacteria and their potential therapeutic effects in human diseases
More information can be found at https://www.mwanlab.com/
Dr Murphy Wan welcomes MRes and PhD students. Please email murphy.wan@port.ac.uk to discuss further.
Research interests
1. Discovery and development of novel therapies against human diseases
2. Emphasis on integration of different omics technologies for in-depth investigation of disease mechanisms and discoveries of novel biomarkers.
Research outputs
2025
Bioavailability and interactions of schisandrin B with 5-fluorouracil in a xenograft mouse model of colorectal cancer
Co, V. A., El-Nezami, H., Lee, P., Wan, M. L. Y., Yang, Y., Zhao, D.
1 Jan 2025, In: Food Chemistry. 463, 9p., 141371
2024
Schisandrin B suppresses colon cancer growth by inducing cell cycle arrest and apoptosis: molecular mechanism and therapeutic potential
Agbodjan-Dossou, R., Co, V. A., Cox, P. A., Dey, P., Draheim, R., El-Nezami, H., Joseph, S., Liu, Y., Sabzichi, M., Twum, B., Wan, M. L. Y.
8 Mar 2024, In: ACS Pharmacology & Translational Science. 7, 3, p. 863-877
BAMLET administration via drinking water inhibits intestinal tumor development and promotes long-term health
Ahmadi, S., Ambite, I., Carneiro, A. N. B. M., Cavalera, M., Chaudhuri, A., Esmaeili, P., Grossi, M., Háček, J., Svanborg, C., Tran, T. H., Wan, M.
15 Feb 2024, In: Scientific Reports. 14, 21p., 3838